Description

Bicyclo[6.1.0]Nonane, 9,9-Difluoro-, trans- (9Ci) is a specialized strained bicyclic organic compound featuring two fluorine atoms on a cyclopropane ring, making it a valuable difluorocyclopropane building block. This high-purity intermediate is critical for introducing the difluorocyclopropane moiety, a key structural motif known to enhance metabolic stability and lipophilicity in bioactive molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for advanced synthesis, including the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Used in the synthesis of drug candidates, particularly where the difluorocyclopropane unit is employed as a bioisostere or to modulate physicochemical properties.
• Agrochemical Research: Serves as a key precursor in developing new pesticides and herbicides with improved efficacy and environmental profiles.
• Material Science: Employed in the creation of specialty polymers and advanced organic materials with unique electronic or structural characteristics.
• Fluorine Chemistry Research: A crucial reagent for studying strain-release reactions and novel fluorination methodologies in academic and industrial R&D settings.
• Ligand and Catalyst Development: Utilized to construct sophisticated, fluorinated ligand frameworks for catalysis and molecular recognition applications.

Basic Information

Product Name	Bicyclo[6.1.0]Nonane, 9,9-Difluoro-, trans- (9Ci)
CAS No.	123883-64-7
Molecular Formula	C9H14F2
Molecular Weight	160.21 g/mol
Synonyms	trans-9,9-Difluorobicyclo[6.1.0]nonane; 9,9-Difluorobicyclo[6.1.0]nonane, trans-; Bicyclo[6.1.0]nonane, 9,9-difluoro-, (1α,6α,8α)-; Difluorocyclopropane-fused bicyclononane; trans-Difluorinated bicyclic alkane
EINECS	Contact for details

Quality Control

We supply Bicyclo[6.1.0]Nonane, 9,9-Difluoro-, trans- (9Ci) in high-purity grades suitable for demanding research and scale-up applications. Our products undergo rigorous quality testing, including chromatographic and spectroscopic analysis, to ensure batch-to-batch consistency and compliance with customer specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This compound should be handled under an inert atmosphere for long-term storage to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0% (Typical 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.