Description

(3R-Cis)-(-)-3-Isopropyl-7A-Methyltetrahydropyrrolo[2,1-B]Oxazol-5(6H)-One is a high-purity, stereochemically defined heterocyclic compound that serves as a critical chiral building block in advanced organic synthesis. Its value lies in its rigid, fused bicyclic structure, which is instrumental for inducing specific stereochemistry in complex target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries who are developing novel active ingredients requiring precise three-dimensional control.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly in antiviral, anti-inflammatory, and central nervous system (CNS) therapeutic areas.
• Asymmetric Catalysis Ligand Precursor: Used to develop novel chiral ligands and organocatalysts for enantioselective transformations.
• Agrochemical Synthesis: Employed in the research and development of stereospecific pesticides and herbicides where biological activity is chirality-dependent.
• Advanced Material Research: Serves as a building block for chiral polymers or liquid crystals with specialized optical properties.
• Academic & Process R&D: A valuable tool for methodological studies in organic chemistry and for scaling up synthetic routes in process chemistry.

Basic Information

Product Name	(3R-Cis)-(-)-3-Isopropyl-7A-Methyltetrahydropyrrolo[2,1-B]Oxazol-5(6H)-One
CAS No.	123808-97-9
Molecular Formula	C11H19NO2
Molecular Weight	197.27 g/mol
Synonyms	(-)-3-Isopropyl-7a-methyltetrahydropyrrolo[2,1-b]oxazol-5(6H)-one; (3R,7aR)-3-(1-Methylethyl)hexahydro-2H-pyrrolo[2,1-b][1,3]oxazol-5-one; (3R-cis)-3-Isopropyl-7a-methyltetrahydropyrrolo[2,1-b]oxazol-5(6H)-one; Chiral Oxazolidinone Derivative; Fused Bicyclic Lactam
EINECS	Contact for details

Quality Control

Our production of (3R-Cis)-(-)-3-Isopropyl-7A-Methyltetrahydropyrrolo[2,1-B]Oxazol-5(6H)-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high enantiomeric purity. All materials are characterized using advanced analytical techniques including chiral HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment, supporting compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.