Description

5-Bromo-4-Chlorothiophene-2-Carboxylic Acid is a high-purity halogenated thiophene derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular structure, which enables the introduction of both bromine and chlorine substituents onto a thiophene carboxylic acid scaffold, facilitating complex molecular transformations. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for molecules targeting central nervous system disorders and infectious diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the thiophene core contributes to biological activity.
• Material Science: Serves as a precursor for functional polymers and organic electronic materials, such as conductive polymers and organic semiconductors.
• Chemical Research: Employed in academic and industrial R&D for studying heterocyclic chemistry, cross-coupling reactions, and structure-activity relationships (SAR).
• Ligand and Catalyst Development: Utilized to create novel ligands for metal catalysis and organocatalysts for asymmetric synthesis.

Basic Information

Product Name	5-Bromo-4-Chlorothiophene-2-Carboxylic Acid
CAS No.	123418-69-9
Molecular Formula	C5H2BrClO2S
Molecular Weight	241.49 g/mol
Synonyms	4-Chloro-5-bromothiophene-2-carboxylic acid; 2-Thiophenecarboxylic acid, 5-bromo-4-chloro-; 5-Bromo-4-chloro-2-thiophenecarboxylic acid; 5-Bromo-4-chlorothiophene-2-carboxylate; 4-Chloro-5-bromo-2-thiophenecarboxylic acid; 5-Br-4-Cl-thiophene-2-COOH; 2-Carboxy-4-chloro-5-bromothiophene
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Chlorothiophene-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the stringent requirements for research and production. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. The material is moisture-sensitive; ensure the container is sealed under an inert atmosphere if specified for high-purity grades.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.