Description

1-(5-Bromo-4-Chloro-2-Thienyl)Ethanone is a high-purity, halogenated thiophene derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique reactivity, enabling the construction of complex heterocyclic frameworks essential for modern material and life sciences. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its halogenated thiophene core for bioactivity.
• Material Science Research: Serves as a precursor for organic electronic materials, including conductive polymers and organic semiconductors (OLED/OFET).
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	1-(5-Bromo-4-Chloro-2-Thienyl)Ethanone
CAS No.	123418-66-6
Molecular Formula	C6H4BrClOS
Molecular Weight	239.52 g/mol
Synonyms	5-Bromo-4-chloro-2-acetylthiophene; 2-Acetyl-5-bromo-4-chlorothiophene; 1-(5-Bromo-4-chloro-2-thienyl)ethan-1-one; 5-Bromo-4-chloro-2-thienyl methyl ketone; Ethanone, 1-(5-bromo-4-chloro-2-thienyl)-; 2-Acetyl-4-chloro-5-bromothiophene; 4-Chloro-5-bromo-2-acetylthiophene
EINECS	Contact for details

Quality Control

Our 1-(5-Bromo-4-Chloro-2-Thienyl)Ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support development from research to commercial scale with a commitment to cGMP and ISO 9001 standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.