Description

Sodium Acetate-13C2-2-D3 is a high-purity, isotopically labeled compound essential for advanced analytical and research applications. This stable isotope-labeled sodium acetate serves as a critical internal standard and tracer, enabling precise quantification and metabolic pathway analysis in complex biological and chemical systems. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, biotechnology, and environmental science sectors for mass spectrometry (MS) and nuclear magnetic resonance (NMR) studies.

Application

• Internal Standard for Mass Spectrometry (MS): Provides accurate quantification of endogenous acetate and related metabolites in bioanalytical assays.
• Metabolic Pathway Tracing: Used in in vitro and in vivo studies to elucidate metabolic fluxes in central carbon metabolism.
• NMR Spectroscopy: Acts as a chemical shift reference or a labeled precursor for synthesizing more complex isotopically labeled molecules for structural analysis.
• Pharmaceutical Research & Development: Critical for drug metabolism and pharmacokinetics (DMPK) studies to track the fate of drug molecules.
• Environmental Analysis: Employed as a tracer in studies of microbial degradation and biogeochemical cycles.
• Biochemical Assay Development: Used to validate and calibrate enzymatic assays involving acetyl-CoA or acetate metabolism.
• Stable Isotope Labeled Compound Synthesis: Serves as a key building block for the synthesis of other 13C and deuterium-labeled fine chemicals and APIs.

Basic Information

Product Name	Sodium Acetate-13C2-2-D3
CAS No.	123333-80-2
Molecular Formula	13C2H2D3NaO2
Molecular Weight	85.06 g/mol (for 13C2, D3 labeled form)
Synonyms	Acetic-13C2-2-d3 Acid Sodium Salt; Sodium Acetate (13C2, 2,2,2-d3); [13C2,2,2,2-2H3]Sodium Acetate; Sodium [13C2]acetate-d3; Sodium Acetate-1,2-13C2,2,2,2-d3; Isotopically Labeled Sodium Acetate; Sodium Acetate (13C2, D3); 13C2-D3-Sodium Acetate
EINECS	Contact for details

Quality Control

Every batch of Sodium Acetate-13C2-2-D3 is manufactured and analyzed under strict quality management systems. We guarantee high chemical and isotopic purity, with comprehensive testing including NMR and MS to confirm isotopic enrichment and positional labeling. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting assay, isotopic purity, chemical purity, and solvent residue levels. Our quality commitment ensures reliability for your most sensitive research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccated conditions or under an inert atmosphere to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 98.0%
Isotopic Purity (13C)	≥ 99 atom % 13C
Isotopic Purity (D)	≥ 98 atom % D
Chemical Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.