Description

3-Thiophen-2-Yl-L-Alanine Hcl CAS NO 123053-24-7 is a non-proteinogenic amino acid derivative featuring a thiophene moiety, making it a valuable chiral building block for advanced synthesis. This compound is essential for researchers and manufacturers developing novel pharmaceuticals and bioactive molecules, particularly in the fields of peptidomimetics and enzyme inhibitors. It is primarily utilized by the pharmaceutical, biotechnology, and agrochemical industries for drug discovery, proteomics research, and the development of diagnostic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for neurological and metabolic disorders.
• Peptidomimetic Design: Used to incorporate the thiophene heterocycle into peptide backbones to enhance stability, bioavailability, and receptor binding affinity.
• Enzyme Inhibitor Synthesis: Serves as a precursor for creating potent and selective inhibitors targeting specific enzymes.
• Agrochemical Research: Employed in the development of novel herbicides, fungicides, and plant growth regulators with improved efficacy.
• Bioconjugation & Labeling: The functional groups allow for site-specific modification of proteins and other biomolecules for diagnostic and therapeutic applications.
• Material Science: Investigated as a monomer or dopant for creating conductive polymers and advanced organic electronic materials.

Basic Information

Product Name	3-Thiophen-2-Yl-L-Alanine Hcl
CAS No.	123053-24-7
Molecular Formula	C7H9NO2S • HCl
Molecular Weight	207.67 g/mol (Free base: 171.22 g/mol)
Synonyms	2-(2-Thienyl)-L-alanine hydrochloride; (S)-2-Amino-3-(2-thienyl)propanoic acid hydrochloride; L-2-Thienylalanine HCl; 3-(2-Thienyl)-L-alanine hydrochloride; β-2-Thienyl-L-alanine hydrochloride; NSC 334910; 3-(Thiophen-2-yl)-L-alanine hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Thiophen-2-Yl-L-Alanine Hcl is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.