Description

3-Thiophenecarboxylic Acid, 5-Acetyl-2-Amino-4-Phenyl-, Et is a high-purity, multifunctional heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, which combines acetyl, amino, phenyl, and carboxylic acid functional groups on a thiophene core, enabling the creation of complex molecules with tailored properties. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as by material scientists exploring functional organic materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiophene scaffold.
• Material Science: Acts as a monomer or functionalizing agent in the production of conductive polymers, organic semiconductors, and non-linear optical (NLO) materials.
• Chemical Synthesis: Employed as a versatile building block for constructing complex heterocyclic systems, ligands for catalysis, and dyes or pigments.
• Academic & Contract Research: Essential for fundamental research in organic chemistry and for contract research organizations (CROs) developing custom synthetic routes.

Basic Information

Product Name	3-Thiophenecarboxylic Acid, 5-Acetyl-2-Amino-4-Phenyl-, Et
CAS No.	122835-45-4
Molecular Formula	C15H13NO3S
Molecular Weight	287.33 g/mol
Synonyms	5-Acetyl-2-amino-4-phenyl-3-thiophenecarboxylic acid ethyl ester; Ethyl 5-acetyl-2-amino-4-phenylthiophene-3-carboxylate; 2-Amino-5-acetyl-4-phenyl-3-thiophenecarboxylic acid ethyl ester; 4-Phenyl-5-acetyl-2-aminothiophene-3-carboxylic acid ethyl ester; 3-Thiophenecarboxylic acid, 2-amino-5-acetyl-4-phenyl-, ethyl ester; 122835-45-4; AAPE; Contact for additional trade names or abbreviations.
EINECS	Contact for details

Quality Control

Our 3-Thiophenecarboxylic Acid, 5-Acetyl-2-Amino-4-Phenyl-, Et is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. For customers with specific purity requirements (e.g., >98%, >99%), custom synthesis and tailored QC protocols are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.2%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.