Description

8-Methoxy-4,9-Dihydro-3H-8-Carboline is a specialized heterocyclic organic compound belonging to the β-carboline alkaloid class, serving as a crucial synthetic intermediate and research chemical. Its unique fused ring structure makes it a valuable scaffold for developing novel pharmaceuticals and bioactive molecules. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, neuroscience research, and the synthesis of complex alkaloids.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of more complex β-carboline derivatives with potential therapeutic applications.
• Medicinal Chemistry Research: Used as a core scaffold in drug discovery programs targeting neurological disorders, cancer, and infectious diseases.
• Neuroscience Studies: Serves as a reference standard or precursor in research related to neurotransmitter receptors and enzyme inhibition.
• Alkaloid Synthesis: Fundamental starting material for the total or semi-synthesis of natural products and alkaloids within the β-carboline family.
• Biochemical Tool Compound: Employed in vitro to study biological pathways and protein interactions due to its specific structural motifs.
• Academic & Industrial R&D: Essential for chemical libraries and exploratory synthesis in both university laboratories and corporate R&D facilities.

Basic Information

Product Name	8-Methoxy-4,9-Dihydro-3H-8-Carboline
CAS No.	122835-08-9
Molecular Formula	C₁₂H₁₂N₂O
Molecular Weight	200.24 g/mol
Synonyms	8-Methoxy-1,2,3,4-tetrahydro-β-carboline; 8-Methoxy-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole; 8-MeO-THβC; 8-Methoxy-tetrahydro-β-carboline; 8-Methoxy-THBC; 8-Methoxy-4,9-dihydro-3H-β-carboline; 8-Methoxy-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole
EINECS	Contact for details

Quality Control

Our 8-Methoxy-4,9-Dihydro-3H-8-Carboline is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maximize stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.