Description

Acrylamide-2,3,3-D3 is a deuterium-labeled isotopologue of acrylamide, a compound of significant interest in analytical and synthetic chemistry. Its primary value lies in its use as a stable, non-radioactive internal standard for mass spectrometry, enabling precise quantification and metabolic tracing studies. This high-purity labeled compound is essential for researchers and quality control laboratories in the pharmaceutical, agrochemical, and environmental testing sectors who require accurate analytical data.

Application

• Internal Standard for LC-MS/MS: Serves as a critical reference standard for the accurate quantification of acrylamide in complex matrices like foodstuffs (e.g., coffee, fried potatoes, baked goods) and environmental samples.
• Metabolic Pathway Tracing: Used in biomedical and pharmacological research to study the absorption, distribution, metabolism, and excretion (ADME) of acrylamide and related compounds.
• Deuterated Synthetic Intermediate: Acts as a building block in the synthesis of more complex deuterium-labeled molecules for research and development.
• Analytical Method Development & Validation: Employed to develop, optimize, and validate sensitive and specific analytical methods for acrylamide detection and measurement.
• Quality Assurance & Control: Provides a traceable standard for ensuring the accuracy and reliability of analytical results in contract research organizations (CROs) and regulatory testing labs.
• Stable Isotope Dilution Assays (SIDA): The gold-standard technique for quantifying acrylamide, where this labeled compound is used to correct for analyte loss during sample preparation.

Basic Information

Product Name	Acrylamide-2,3,3-D3
CAS No.	122775-19-3
Molecular Formula	C₃H₂D₃NO
Molecular Weight	74.09 g/mol
Synonyms	2-Propenamide-2,3,3-d3; Acrylamide-d3; [2,3,3-²H₃]Acrylamide; Deuterated Acrylamide; Acrylamide (D3); Acrylamide-2,3,3-d₃; (²H₃)Acrylamide; 2,3,3-Trideuteroacrylamide
EINECS	Contact for details

Quality Control

Every batch of Acrylamide-2,3,3-D3 is manufactured and tested under strict quality management systems. We guarantee high chemical and isotopic purity, with comprehensive testing including NMR and mass spectrometry to confirm deuteration level and identity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, assay, and solvent content to ensure it meets the exacting standards required for analytical and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.