Description

1-Azabicyclo[2.2.1]Heptan-3-One Hydrochloride is a high-purity organic salt and a key advanced pharmaceutical intermediate. This compound is valued for its rigid bicyclic structure, which serves as a crucial scaffold in modern medicinal chemistry for developing novel therapeutics. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the synthesis of complex active pharmaceutical ingredients (APIs) and drug candidates.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex drug molecules, particularly those targeting neurological and cardiovascular systems.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Organic Synthesis: Serves as a precursor for synthesizing other complex heterocyclic compounds and chiral ligands.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects and scale-up development.
• Academic Research: Utilized in university and institutional labs for advanced organic chemistry studies and methodology development.

Basic Information

Product Name	1-Azabicyclo[2.2.1]Heptan-3-One Hydrochloride
CAS No.	122737-66-0
Molecular Formula	C6H9NO·HCl
Molecular Weight	147.60 g/mol
Synonyms	1-Aza-3-oxobicyclo[2.2.1]heptane Hydrochloride; 3-Oxo-1-azabicyclo[2.2.1]heptane Hydrochloride; 1-Azabicyclo[2.2.1]heptan-3-one HCl; 2-Oxoniabicyclo[2.2.1]heptan-3-one Chloride; 3-Quinuclidinone Hydrochloride (common name); Tropinone Hydrochloride (related structure); Endo-1-Azabicyclo[2.2.1]heptan-3-one Hydrochloride
EINECS	Contact for details

Quality Control

Our 1-Azabicyclo[2.2.1]Heptan-3-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical R&D and process development. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.