Description

5-Hydroxy-2-Amino-3-Methylimidazo(4,5-F)Quinoline is a high-purity heterocyclic aromatic amine of significant interest in advanced research and development. This compound serves as a critical building block and reference standard in the study of mutagenic and carcinogenic processes. It is primarily utilized by research institutions and quality control laboratories in the pharmaceutical, food safety, and environmental toxicology sectors for analytical method development and validation.

Application

• Analytical Reference Standard: Used as a certified standard for the quantification of heterocyclic aromatic amines (HAAs) in complex matrices via HPLC, LC-MS, or GC-MS.
• Biomedical Research: Employed in studies investigating the metabolic activation, DNA adduct formation, and carcinogenic mechanisms of food-borne mutagens.
• Food Safety & Toxicology: Essential for developing and validating analytical methods to detect and monitor HAAs in cooked meat products and other processed foods.
• Pharmaceutical Impurity Profiling: Acts as a potential impurity reference compound in the synthesis and quality control of related pharmaceutical intermediates.
• Environmental Analysis: Applied in research to understand the environmental fate and impact of persistent aromatic amines.
• Method Development & Validation: Serves as a key analyte for calibrating instrumentation and establishing regulatory-compliant testing protocols in analytical laboratories.

Basic Information

Product Name	5-Hydroxy-2-Amino-3-Methylimidazo(4,5-F)Quinoline
CAS No.	122719-38-4
Molecular Formula	C11H10N4O
Molecular Weight	214.22 g/mol
Synonyms	5-Hydroxy-2-Amino-3-Methyl-IQ; 5-OH-2-Amino-3-Methylimidazo[4,5-f]quinoline; 2-Amino-3-methyl-5-hydroxyimidazo[4,5-f]quinoline; 5-Hydroxy-IQ; 5-OH-IQ; 5-Hydroxy-2-Amino-3-Methyl-IQ; HAAs Reference Standard; Mutagenic Heterocyclic Amine Standard
EINECS	Contact for details

Quality Control

Our 5-Hydroxy-2-Amino-3-Methylimidazo(4,5-F)Quinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR, MS), to ensure it meets the high standards required for research and analytical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.