Description

3(4H)-Isoquinolinone,1-Ethoxy-4A,7,8,8A-Tetrahydro-5-Methyl-,cis-(9Ci) is a specialized heterocyclic organic compound of significant interest in advanced chemical synthesis. This cis-configured molecule serves as a versatile and high-purity building block for the development of novel active pharmaceutical ingredients (APIs) and complex fine chemicals. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and material science sectors.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and anti-infective drugs.
• Agrochemical Synthesis: Used as a precursor in the creation of novel pesticides and herbicides with specific stereochemical requirements.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a core structure for developing advanced electron-transport or host materials in display technologies.
• Ligand for Catalysis: Employed in the synthesis of chiral ligands for asymmetric catalysis, enhancing the efficiency of stereoselective reactions.
• Academic & Industrial R&D: Serves as a standard or starting material for methodological studies in organic chemistry and process development.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Item	Details
Product Name	3(4H)-Isoquinolinone,1-Ethoxy-4A,7,8,8A-Tetrahydro-5-Methyl-,cis-(9Ci)
CAS No.	122490-25-9
Molecular Formula	C₁₂H₁₇NO₂
Molecular Weight	207.27 g/mol
Synonyms	cis-1-Ethoxy-5-methyl-1,4a,7,8-tetrahydro-3(4H)-isoquinolinone; 1-Ethoxy-5-methyl-cis-1,4a,7,8-tetrahydroisoquinolin-3(4H)-one; 1,4a,7,8-Tetrahydro-1-ethoxy-5-methyl-3(4H)-isoquinolinone, cis-; (4aR,8aS)-1-Ethoxy-5-methyl-1,4a,7,8-tetrahydro-3H-isoquinolin-3-one; (cis)-1-Ethoxy-5-methyl-4a,7,8,8a-tetrahydro-3(4H)-isoquinolinone
EINECS	Contact for details

Quality Control

Every batch of our 3(4H)-Isoquinolinone derivative is produced under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and chiral integrity. A comprehensive Certificate of Analysis (COA) detailing purity, chiral excess, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (cis-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.