Description

Monomethyl-2-(2-Thienylmethyl)-Malonate is a specialized malonate ester derivative featuring a thienylmethyl substituent, serving as a crucial synthetic intermediate in advanced organic synthesis. Its molecular architecture makes it a valuable building block for constructing complex heterocyclic and pharmaceutical compounds. This high-purity intermediate is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing thiophene or malonate-derived pharmacophores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic component.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and organic electronic materials.
• Chemical Research & Development: A versatile building block for constructing complex molecular libraries in medicinal chemistry and process development.
• Fine Chemical Production: Employed in multi-step synthesis for producing high-value, low-volume specialty chemicals.

Basic Information

Product Name	Monomethyl-2-(2-Thienylmethyl)-Malonate
CAS No.	122308-24-1
Molecular Formula	C10H12O4S
Molecular Weight	228.26 g/mol
Synonyms	Monomethyl 2-[(thiophen-2-yl)methyl]propanedioate; 2-(Thiophen-2-ylmethyl)malonic acid monomethyl ester; Methyl 2-((thiophen-2-yl)methyl)malonate; Propanedioic acid, 2-[(2-thienyl)methyl]-, monomethyl ester; (2-Thienylmethyl)malonic Acid Monomethyl Ester
EINECS	Contact for details

Quality Control

Our Monomethyl-2-(2-Thienylmethyl)-Malonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.