Description

2-(3-Bromophenyl)-1,1,1-Trifluoropropan-2-Ol is a high-value fluorinated and brominated aromatic building block. This compound is essential for advanced organic synthesis, offering versatile reactivity for constructing complex molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly those requiring trifluoromethyl and aryl bromide functional groups for bioactivity and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides where the bromophenyl and trifluoromethyl motifs are critical for efficacy.
• Ligand and Catalyst Development: Serves as a precursor for sophisticated ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials due to its unique electronic properties.
• Cross-Coupling Reactions: The aryl bromide moiety makes it an excellent substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Fluorine Chemistry Studies: A valuable compound for investigating the influence of the trifluoromethyl group on chemical reactivity and physical properties.

Basic Information

Product Name	2-(3-Bromophenyl)-1,1,1-Trifluoropropan-2-Ol
CAS No.	122243-30-5
Molecular Formula	C9H8BrF3O
Molecular Weight	269.06 g/mol
Synonyms	1-(3-Bromophenyl)-2,2,2-trifluoroethanol; 2,2,2-Trifluoro-1-(3-bromophenyl)ethanol; α-(Trifluoromethyl)-3-bromobenzyl alcohol; 3-Bromo-α-(trifluoromethyl)benzyl alcohol; 1-(3-Bromophenyl)-2,2,2-trifluoroethan-1-ol; 2-(3-Bromophenyl)-1,1,1-trifluoro-2-propanol; 3-Bromophenyl trifluoromethyl carbinol
EINECS	Contact for details

Quality Control

Every batch of 2-(3-Bromophenyl)-1,1,1-Trifluoropropan-2-Ol is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistent lot-to-lot performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids, strong bases, and oxidizing agents. The compound may be hygroscopic (moisture-sensitive); handle and store under an inert atmosphere such as nitrogen for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.