Description

7-Nitro-3-Phenyl-1H-Indole-2-Carboxylic Acid is a high-purity, functionalized indole derivative that serves as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both nitro and carboxylic acid functional groups on the indole core, makes it an invaluable precursor for the development of novel pharmacologically active compounds. This intermediate is primarily sought after by research institutions and pharmaceutical companies engaged in the discovery and development of new therapeutic agents, particularly in areas requiring complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators that leverage the indole structure.
• Material Science: Serves as a precursor for organic semiconductors, dyes, and photoactive materials due to its electron-withdrawing nitro group and planar aromatic system.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in heterocyclic chemistry and the construction of complex molecular libraries.
• Bioconjugation Chemistry: The carboxylic acid group enables its use in coupling reactions to create labeled probes or conjugate molecules for biochemical studies.

Basic Information

Product Name	7-Nitro-3-Phenyl-1H-Indole-2-Carboxylic Acid
CAS No.	121983-01-5
Molecular Formula	C15H10N2O4
Molecular Weight	282.25 g/mol
Synonyms	2-Carboxy-7-nitro-3-phenylindole; 3-Phenyl-7-nitro-1H-indole-2-carboxylic acid; 7-Nitro-3-phenylindole-2-carboxylic acid; 1H-Indole-2-carboxylic acid, 7-nitro-3-phenyl-; 7-Nitro-3-phenyl-1H-indole-2-carboxylic acid; 2-Indolecarboxylic acid, 7-nitro-3-phenyl-
EINECS	Contact for details

Quality Control

Every batch of 7-Nitro-3-Phenyl-1H-Indole-2-Carboxylic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.