Description

2-(Cyclohexylcarbonyl)-4-Oxo-1,2,3,4,6,7,8,12B-Octahydropyrazino(2,1-A)(2)Benzazepine is a complex heterocyclic organic compound that serves as a critical advanced intermediate in modern pharmaceutical synthesis. Its intricate fused-ring structure makes it a valuable building block for developing novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. This high-purity intermediate is essential for research and development laboratories and production facilities focused on innovative drug discovery, particularly in central nervous system (CNS) and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step production of novel therapeutic compounds and active pharmaceutical ingredients (APIs).
• Drug Discovery & Research: Used in medicinal chemistry for the design, synthesis, and screening of new chemical entities with potential biological activity.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects.
• Academic & Institutional Research: Utilized in university and institutional laboratories for advanced organic synthesis and pharmacological studies.
• Building Block for Fused Heterocycles: Serves as a sophisticated scaffold for constructing more complex polycyclic molecular architectures.

Basic Information

Product Name	2-(Cyclohexylcarbonyl)-4-Oxo-1,2,3,4,6,7,8,12B-Octahydropyrazino(2,1-A)(2)Benzazepine
CAS No.	121654-56-6
Molecular Formula	C22H28N2O2
Molecular Weight	352.47 g/mol
Synonyms	2-(Cyclohexylcarbonyl)-4-oxo-1,2,3,4,6,7,8,12b-octahydropyrazino[2,1-a][2]benzazepine; Octahydropyrazino(2,1-a)(2)benzazepine-2-carboxylic acid, 4-oxo-, cyclohexyl ester; 4-Oxo-2-(cyclohexylcarbonyl)-1,2,3,4,6,7,8,12b-octahydropyrazino[2,1-a][2]benzazepine; CAS 121654-56-6; Pyrazino[2,1-a][2]benzazepine derivative
EINECS	Contact for details

Quality Control

Our production of 2-(Cyclohexylcarbonyl)-4-Oxo-1,2,3,4,6,7,8,12B-Octahydropyrazino(2,1-A)(2)Benzazepine adheres to stringent quality management systems, ensuring batch-to-batch consistency and high purity suitable for pharmaceutical R&D. All materials are subjected to rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support compliance with cGMP guidelines for advanced intermediates and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed to protect the material from moisture absorption. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.