Description

3-Thiophenecarboxamide, n-(6-Amino-1,2,3,4-Tetrahydro-1,3-Dimethyl-2,4-Dioxo-5-Pyrimidinyl)- is a high-purity, heterocyclic organic compound that serves as a critical advanced intermediate in pharmaceutical research and development. Its unique molecular architecture, combining thiophene and pyrimidinone moieties, makes it a valuable building block for synthesizing novel active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antiviral compounds.
• Agrochemical Research: Used as a building block for developing new pesticides and herbicides with specific biological activity profiles.
• Material Science: Potential monomer or additive in the development of specialty polymers and organic electronic materials due to the thiophene unit.
• Chemical Biology & Proteomics: Serves as a scaffold or linker in the design of chemical probes and enzyme inhibitors for biochemical research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this precise heterocyclic structure.
• Academic Research: Utilized in university and institutional labs for methodological studies in heterocyclic chemistry and medicinal chemistry programs.

Basic Information

Item	Details
Product Name	3-Thiophenecarboxamide, n-(6-Amino-1,2,3,4-Tetrahydro-1,3-Dimethyl-2,4-Dioxo-5-Pyrimidinyl)-
CAS No.	121543-18-8
Molecular Formula	C11H12N4O3S
Molecular Weight	280.30 g/mol
Synonyms	N-(6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl)-3-thiophenecarboxamide; 5-Pyrimidinecarboxamide, 6-amino-1,2,3,4-tetrahydro-1,3-dimethyl-2,4-dioxo-, N-3-thienyl-; 6-Amino-1,3-dimethyl-5-[(3-thienylcarbonyl)amino]uracil; 3-[(6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl)carbamoyl]thiophene; 121543-18-8; 3-Thiophenecarboxamide, N-(6-amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl)-
EINECS	Contact for details

Quality Control

Our 3-Thiophenecarboxamide, n-(6-Amino-1,2,3,4-Tetrahydro-1,3-Dimethyl-2,4-Dioxo-5-Pyrimidinyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.