Description

Hexanedioic-3,3,4,4-D4 Acid is a deuterium-labeled analog of adipic acid, a key dicarboxylic acid. This isotopically labeled compound is essential for advanced analytical and research applications where precise molecular tracking is required. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for use as an internal standard in mass spectrometry, metabolic studies, and the synthesis of labeled polymers.

Application

• Internal Standard for Quantitative Analysis: Used in LC-MS and GC-MS for the accurate quantification of adipic acid and related metabolites in complex biological and environmental matrices.
• Metabolic Pathway Tracing: Serves as a stable isotope tracer in pharmacokinetic, drug metabolism, and biochemical pathway studies.
• Synthesis of Deuterated Materials: A key precursor for the synthesis of deuterium-labeled polymers, such as nylons, to study polymer properties and degradation mechanisms.
• NMR Spectroscopy: Provides a non-radioactive probe for structural elucidation and reaction mechanism studies via Nuclear Magnetic Resonance spectroscopy.
• Pharmaceutical Research: Employed in the development and validation of analytical methods for drug substances and impurities.
• Environmental Analysis: Acts as a tracer in studies monitoring the environmental fate and biodegradation of adipic acid and its derivatives.

Basic Information

Product Name	Hexanedioic-3,3,4,4-D4 Acid
CAS No.	121311-78-2
Molecular Formula	C6D4H6O4
Molecular Weight	150.16 g/mol
Synonyms	Adipic-3,3,4,4-d4 Acid; [3,3,4,4-2H4]Adipic Acid; 1,4-Dicarboxy-1,2,3,4-tetradeuteriobutane; 1,6-Hexanedioic-3,3,4,4-d4 Acid; Deuterated Adipic Acid; Hexanedioic-d4 Acid; Butane-1,4-dicarboxylic-3,3,4,4-d4 Acid
EINECS	Contact for details

Quality Control

Our Hexanedioic-3,3,4,4-D4 Acid is produced under strict quality management protocols. Each batch is characterized to ensure high chemical purity and isotopic enrichment, typically exceeding 98 atom % D. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing specifications for assay, isotopic purity, and identity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and analytical performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Isotopic Purity (NMR/MS)	≥ 98 atom % D
Chemical Purity	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.