Description

1H-Indole-2-Carboxylic Acid,3-Formyl-5,6-Dimethoxy-,Ethyl Ester is a high-value, multi-functional indole derivative that serves as a critical advanced intermediate in organic synthesis. Its unique molecular structure, featuring both formyl and ester functional groups on the indole core, makes it indispensable for constructing complex heterocyclic systems. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, particularly in the development of kinase inhibitors, anti-cancer agents, and central nervous system (CNS) active compounds.
• Agrochemical Research: Used in the creation of novel herbicides, fungicides, and plant growth regulators, leveraging the bioactivity of the indole scaffold.
• Organic Synthesis & Material Science: Serves as a versatile precursor for synthesizing complex organic molecules, dyes, and functional materials due to its reactive aldehyde and ester groups.
• Academic & Contract Research: Essential for medicinal chemistry programs and methodological studies in universities and contract research organizations (CROs).
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals and high-value intermediates for various industrial applications.

Basic Information

Item	Details
Product Name	1H-Indole-2-Carboxylic Acid,3-Formyl-5,6-Dimethoxy-,Ethyl Ester
CAS No.	121282-80-2
Molecular Formula	C₁₄H₁₅NO₅
Molecular Weight	277.27 g/mol
Synonyms	Ethyl 3-Formyl-5,6-dimethoxyindole-2-carboxylate; 3-Formyl-5,6-dimethoxy-1H-indole-2-carboxylic Acid Ethyl Ester; 5,6-Dimethoxy-3-formylindole-2-carboxylic Acid Ethyl Ester; 1H-Indole-2-carboxylic acid, 3-formyl-5,6-dimethoxy-, ethyl ester; Ethyl 5,6-dimethoxy-3-formyl-1H-indole-2-carboxylate; 121282-80-2; 3-Formyl-5,6-dimethoxyindole-2-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 1H-Indole-2-Carboxylic Acid,3-Formyl-5,6-Dimethoxy-,Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports applications in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.