Description

Methyl 5-Methoxy-α-Oxo-1-(Phenylsulfonyl)Indole-2-Acetate is a high-purity, advanced pharmaceutical intermediate characterized by its complex indole-based molecular structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting specific receptor pathways. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, where precise chemical structure and reliable purity are critical for successful outcomes.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug candidates, especially in medicinal chemistry research.
• API Development: Used in the research and development of new Active Pharmaceutical Ingredients (APIs) for potential therapeutic applications.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for constructing complex heterocyclic compounds due to its reactive functional groups.
• Biochemical Research: Utilized in studies investigating enzyme inhibitors or modulators that interact with indole-based structures.
• Process Chemistry: Applied in scaling up synthetic routes from laboratory to pilot plant scale for potential commercial drug production.

Basic Information

Product Name	Methyl 5-Methoxy-α-Oxo-1-(Phenylsulfonyl)Indole-2-Acetate
CAS No.	121268-84-6
Molecular Formula	C19H17NO6S
Molecular Weight	387.41 g/mol
Synonyms	Methyl 5-methoxy-α-oxo-1-(phenylsulfonyl)-1H-indole-2-acetate; 1H-Indole-2-acetic acid, 5-methoxy-α-oxo-1-(phenylsulfonyl)-, methyl ester; Methyl (5-methoxy-α-oxo-1-tosylindol-2-yl)acetate; 1-(Phenylsulfonyl)-5-methoxy-2-(methoxycarbonylmethyl)-1H-indole-3-carbaldehyde (tautomeric form); 121268-84-6; Methyl 1-(benzenesulfonyl)-5-methoxy-2-oxoindole-3-acetate
EINECS	Contact for details

Quality Control

Our production of Methyl 5-Methoxy-α-Oxo-1-(Phenylsulfonyl)Indole-2-Acetate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All materials are subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all test results are provided with each shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be sensitive to prolonged exposure to moisture and should be handled under inert conditions if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.