Description

(1R,2S,4S)-Bicyclo[2.2.1]Heptan-2-Amine Hydrochloride is a high-purity, chiral amine hydrochloride salt, a key building block in advanced organic synthesis. Its rigid bicyclic framework and defined stereochemistry make it an invaluable intermediate for constructing complex molecules with precise three-dimensional architecture. This compound is essential for research and development in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients, chiral catalysts, and ligands.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the development of new active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and antiviral drug candidates.
• Asymmetric Catalysis: Used as a precursor for synthesizing chiral ligands and organocatalysts, enabling enantioselective transformations in fine chemical production.
• Agrochemical Synthesis: Serves as a building block for creating novel, stereochemically defined pesticides and herbicides with improved efficacy and environmental profiles.
• Material Science Research: Employed in the development of advanced polymers and functional materials where its rigid structure imparts specific mechanical or chemical properties.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, medicinal chemistry, and total synthesis projects.

Basic Information

Product Name	(1R,2S,4S)-Bicyclo[2.2.1]Heptan-2-Amine Hydrochloride
CAS No.	121122-83-6
Molecular Formula	C7H14ClN
Molecular Weight	147.65 g/mol
Synonyms	(1R,2S,4S)-2-Aminonorbornane Hydrochloride; endo-(1R,2S,4S)-2-Aminobicyclo[2.2.1]heptane Hydrochloride; (1R,2S,4S)-2-Norbornanamine Hydrochloride; endo-2-Aminonorbornane Hydrochloride (specified isomer); Bicyclo[2.2.1]heptan-2-amine, (1R,2S,4S)-, hydrochloride; endo-Norcamphamine Hydrochloride
EINECS	Contact for details

Quality Control

Our (1R,2S,4S)-Bicyclo[2.2.1]Heptan-2-Amine Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including chiral purity analysis, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.