Description

Dimethyl 4-Aminothiophene-2,3-Dicarboxylate Hydrochloride is a high-purity, functionalized thiophene derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex heterocyclic scaffolds, enabling the development of novel materials and active pharmaceutical ingredients. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for process development and scale-up.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the thiophene core for bioactivity.
• Material Science Research: Serves as a monomer or functional unit in the development of conductive polymers, organic semiconductors, and other advanced electronic materials.
• Dye and Pigment Chemistry: Acts as a building block for creating novel heterocyclic dyes and organic pigments with specific light-absorption properties.
• Academic & Industrial R&D: Employed in medicinal chemistry and process chemistry laboratories for lead optimization and route scouting.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke fine chemicals for client projects.

Basic Information

Product Name	Dimethyl 4-Aminothiophene-2,3-Dicarboxylate Hydrochloride
CAS No.	121071-71-4
Molecular Formula	C8H10ClNO4S
Molecular Weight	251.69 g/mol
Synonyms	4-Amino-2,3-thiophenedicarboxylic Acid Dimethyl Ester Hydrochloride; Dimethyl 4-Amino-2,3-thiophenedicarboxylate Hydrochloride; 2,3-Thiophenedicarboxylic Acid, 4-Amino-, Dimethyl Ester, Hydrochloride; Methyl 4-Aminothiophene-2,3-dicarboxylate Hydrochloride; 4-Aminothiophene-2,3-dicarboxylic Acid Dimethyl Ester HCl
EINECS	Contact for details

Quality Control

Our Dimethyl 4-Aminothiophene-2,3-Dicarboxylate Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can tailor quality protocols to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions (e.g., nitrogen atmosphere) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.