Description

1H-Indazole-3-Carboxamide, 1-Methyl-n-[(3-Endo)-9-Methyl-9-Azabicyclo[3.3.1]Non-3-Yl]- is a high-purity, advanced pharmaceutical intermediate characterized by its complex, rigid bicyclic structure. This compound is of significant value for medicinal chemistry research and development, particularly in the synthesis of novel therapeutic agents targeting the central nervous system. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new drug candidates, especially those exploring modulators of neurological receptors.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Preclinical Development: Serves as a critical material for producing batches of experimental compounds for pharmacological and toxicological evaluation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the biopharma industry.
• Reference Standard: Can be utilized as an analytical standard for method development and quality control in API manufacturing.

Basic Information

Product Name	1H-Indazole-3-Carboxamide, 1-Methyl-n-[(3-Endo)-9-Methyl-9-Azabicyclo[3.3.1]Non-3-Yl]-
CAS No.	121061-98-1
Molecular Formula	C18H24N4O
Molecular Weight	312.41 g/mol
Synonyms	1-Methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide; 9-Methyl-3-endo-[N-(1-methyl-1H-indazol-3-yl)carbonyl]-9-azabicyclo[3.3.1]nonane; PF-04455242; PF 04455242; PF04455242; (3-endo)-9-Methyl-3-[[(1-methyl-1H-indazol-3-yl)carbonyl]amino]-9-azabicyclo[3.3.1]nonane
EINECS	Contact for details

Quality Control

Our 1H-Indazole-3-Carboxamide, 1-Methyl-n-[(3-Endo)-9-Methyl-9-Azabicyclo[3.3.1]Non-3-Yl]- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.