Description

(S)-Indoline-2-Carboxylic Acid Benzyl Ester is a chiral, non-proteinogenic amino acid derivative that serves as a crucial building block in organic synthesis. This compound matters for its role as a key intermediate in the preparation of complex pharmaceutical agents and bioactive molecules, enabling the introduction of the indoline scaffold with defined stereochemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new drugs, particularly in areas requiring high stereochemical purity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of protease inhibitors, receptor antagonists, and other active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Used in the construction of complex natural products and medicinal chemistry compounds where the (S)-configuration is required for biological activity.
• Peptidomimetics Research: Serves as a constrained proline analog in the design and synthesis of novel peptide-like molecules for drug discovery.
• Chemical Biology Probes: Utilized in the development of tool compounds and labeled ligands for studying enzyme mechanisms and biological pathways.
• Catalyst and Ligand Development: Can be employed as a precursor for chiral catalysts or ligands used in enantioselective transformations.

Basic Information

Item	Detail
Product Name	(S)-Indoline-2-Carboxylic Acid Benzyl Ester
CAS No.	120925-75-9
Molecular Formula	C16H15NO2
Molecular Weight	253.30 g/mol
Synonyms	(S)-1,2-Dihydroindole-2-carboxylic acid benzyl ester; (S)-Indoline-2-carboxylic acid phenylmethyl ester; Benzyl (S)-indoline-2-carboxylate; (S)-2-Carboxyindoline benzyl ester; (S)-Benzyl 2,3-dihydro-1H-indole-2-carboxylate; (S)-Indoline-2-carboxylic acid, benzyl ester; (2S)-2,3-Dihydro-1H-indole-2-carboxylic acid benzyl ester
EINECS	Contact for details

Quality Control

Our (S)-Indoline-2-Carboxylic Acid Benzyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical and enantiomeric purity, consistent with standards for advanced pharmaceutical intermediates. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. Due to its light-sensitive nature, handling should minimize exposure to strong light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.