Description

5-(Aminomethyl)Thiophene-2-Carboxylic Acid is a versatile bifunctional organic building block containing both a carboxylic acid and a primary amine group on a thiophene scaffold. This unique structure makes it a critical intermediate for synthesizing complex molecules with tailored properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging the thiophene moiety for bioactivity.
• Ligand and Chelator Preparation: Serves as a starting material for creating specialized ligands in catalysis and metal-chelating agents for industrial processes.
• Polymer and Material Science: Incorporated into monomers for producing specialty polymers, conductive materials, or coatings with unique electronic characteristics.
• Peptide Mimetics and Bioconjugation: The amine and acid functionalities allow for its use in constructing peptide analogs or as a linker in bioconjugation chemistry.
• Research & Development: A valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.

Basic Information

Item	Details
Product Name	5-(Aminomethyl)Thiophene-2-Carboxylic Acid
CAS No.	120889-75-0
Molecular Formula	C7H7NO2S
Molecular Weight	169.20 g/mol
Synonyms	2-Thiophenecarboxylic acid, 5-(aminomethyl)-; 5-(Aminomethyl)-2-thiophenecarboxylic acid; 5-(Aminomethyl)thiophene-2-carboxylic acid; 2-Carboxy-5-aminomethylthiophene; (5-Aminomethyl)thiophene-2-carboxylic acid; 5-Carbamoylmethylthiophene-2-carboxylic acid (common misnomer); AMTCA; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our production of 5-(Aminomethyl)Thiophene-2-Carboxylic Acid adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with global regulatory frameworks, including REACH, and can tailor quality specifications to meet specific customer requirements for research or cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.