Description

(E)-Ceftiofur is a third-generation cephalosporin antibiotic specifically designed for veterinary use. Its core value lies in its potent, broad-spectrum activity against Gram-positive and Gram-negative bacteria, making it a critical tool for managing respiratory, urinary, and soft tissue infections in livestock. This product is essential for manufacturers in the animal health pharmaceutical industry, formulators of veterinary injectable solutions, and suppliers to large-scale livestock and poultry operations globally.

Application

• Veterinary Pharmaceutical Manufacturing: Primary active pharmaceutical ingredient (API) for injectable antibiotic formulations.
• Treatment of Bovine Respiratory Disease (BRD): A key therapeutic for pneumonia in cattle caused by Mannheimia haemolytica, Pasteurella multocida, and Histophilus somni.
• Swine Health Management: Used for the treatment and control of swine respiratory disease and other bacterial infections.
• Poultry Antibiotic Therapy: Effective against specific bacterial pathogens in poultry when administered under veterinary guidance.
• Metritis and Mastitis Control: Treatment of uterine infections in cattle and mastitis in dairy cows.
• Foot Rot and Diphtheria Treatment: Management of interdigital necrobacillosis (foot rot) in cattle.
• Research & Development: Reference standard for analytical method development, quality control, and pharmacological studies.

Basic Information

Product Name	(E)-Ceftiofur
CAS No.	120882-20-4
Molecular Formula	C19H17N5O7S3
Molecular Weight	523.56 g/mol
Synonyms	Ceftiofur (E)-isomer; Ceftiofur Sodium; (6R,7R)-7-[[(2Z)-2-(2-Amino-4-thiazolyl)-2-methoxyiminoacetyl]amino]-3-[(2-furanylcarbonyl)thiomethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; U-64279E; Excenel; Excede; Naxcel
EINECS	Contact for details

Quality Control

Our (E)-Ceftiofur is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for veterinary pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming specifications for identity, purity, and related substances. We adhere to cGMP principles to ensure consistent quality and reliable supply for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Specific Optical Rotation	+52° to +58° (c=1, in water)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.