Description

(3,4-Dihydro-1H-Isoquinolin-2-Yl)-Piperidin-4-Yl-Methanone CAS NO 120848-76-2 is a high-purity, heterocyclic organic compound featuring a unique molecular scaffold that combines isoquinoline and piperidine pharmacophores. This structure makes it a valuable advanced pharmaceutical intermediate and a critical building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Chemical Synthesis Building Block: Employed in the development of complex molecules for agrochemical and material science applications.
• Biochemical Tool Compound: Acts as a research chemical for investigating biological pathways and enzyme interactions in academic and industrial settings.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring this specific heterocyclic core.

Basic Information

Product Name	(3,4-Dihydro-1H-Isoquinolin-2-Yl)-Piperidin-4-Yl-Methanone
CAS No.	120848-76-2
Molecular Formula	C15H18N2O
Molecular Weight	242.32 g/mol
Synonyms	4-[(3,4-Dihydro-1H-isoquinolin-2-yl)carbonyl]piperidine; 1-(3,4-Dihydroisoquinolin-2-yl)-4-piperidinylmethanone; 2-(4-Piperidinylcarbonyl)-1,2,3,4-tetrahydroisoquinoline; (3,4-Dihydro-2H-isoquinolin-1-yl)(piperidin-4-yl)methanone; Piperidine, 4-[(3,4-dihydro-1H-isoquinolin-2-yl)carbonyl]-; 120848-76-2; (Tetrahydroisoquinolin-2-yl)(4-piperidyl)methanone
EINECS	Contact for details

Quality Control

Our (3,4-Dihydro-1H-Isoquinolin-2-Yl)-Piperidin-4-Yl-Methanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our clients' pharmaceutical development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.