Description

(4-(tert-Butyldimethylsilanyloxy)Phenyl)Phenylmethanone is a high-purity, protected phenol derivative featuring a tert-butyldimethylsilyl (TBDMS) ether group. This compound matters as a versatile and crucial synthetic intermediate, offering chemoselective protection for phenolic hydroxyl groups during complex multi-step organic syntheses. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures, particularly in the synthesis of active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and plant growth regulators.
• Advanced Material Precursor: Serves as a monomer or intermediate in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Organic Synthesis Research: A valuable reagent in academic and industrial R&D labs for methodology development and total synthesis projects.
• Protecting Group Chemistry: Specifically employed for the temporary protection of phenolic -OH groups under a wide range of reaction conditions.
• Fine Chemical Production: Integral to the manufacture of dyes, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	(4-(tert-Butyldimethylsilanyloxy)Phenyl)Phenylmethanone
CAS No.	120727-58-4
Molecular Formula	C19H24O2Si
Molecular Weight	312.48 g/mol
Synonyms	4-(tert-Butyldimethylsilyloxy)benzophenone; [4-[(1,1-Dimethylethyl)dimethylsilyl]oxy]phenyl]phenyl-methanone; 4-(TBDMSO)benzophenone; 4-(tert-Butyldimethylsiloxy)benzophenone; Benzophenone, 4-[(1,1-dimethylethyl)dimethylsilyl]oxy]-; 4-Hydroxybenzophenone TBDMS ether; 4-Benzoylphenyl tert-butyldimethylsilyl ether
EINECS	Contact for details

Quality Control

Our (4-(tert-Butyldimethylsilanyloxy)Phenyl)Phenylmethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.