Description

3-(Carboxymethyl)-5-Chloro-1H-Indole-2-Carboxylic Acid is a high-purity, functionalized indole derivative serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a chlorinated indole core and a carboxymethyl side chain, makes it an essential precursor for developing novel active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Organic Synthesis Building Block: Employed in constructing complex heterocyclic compounds for material science and chemical research.
• Bioconjugation & Probe Development: Serves as a starting material for creating fluorescent probes or affinity labels used in biochemical assays.
• Peptidomimetic Chemistry: Incorporated into peptide analogs to modulate stability, bioavailability, and receptor binding.

Basic Information

Product Name	3-(Carboxymethyl)-5-Chloro-1H-Indole-2-Carboxylic Acid
CAS No.	120716-95-2
Molecular Formula	C11H8ClNO4
Molecular Weight	253.64 g/mol
Synonyms	5-Chloro-3-(carboxymethyl)-1H-indole-2-carboxylic acid; 5-Chloro-1H-indole-2,3-dicarboxylic acid 3-(carboxymethyl) ester; 3-Carboxymethyl-5-chloroindole-2-carboxylic acid; 120716-95-2; 5-Chloro-3-(carboxymethyl)indole-2-carboxylic acid; 2-Carboxy-5-chloro-3-indoleacetic acid
EINECS	Contact for details

Quality Control

Our 3-(Carboxymethyl)-5-Chloro-1H-Indole-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.