Description

Trefentanil is a potent synthetic opioid analgesic belonging to the 4-anilidopiperidine class. This high-purity compound is of significant interest in advanced pharmaceutical research and development, particularly for studying opioid receptor pharmacology. It serves as a critical reference standard and intermediate for specialized laboratories and manufacturers engaged in the development of analgesic agents and receptor studies. Trefentanil CAS NO 120656-93-1 is essential for applications requiring precise chemical characterization and pharmacological evaluation.

Application

• Pharmaceutical Reference Standard: Used as a certified analytical standard for quality control and method validation in drug testing and forensic analysis.
• Biomedical Research: A key tool in preclinical studies for investigating the mechanisms, binding affinity, and structure-activity relationships (SAR) of opioid receptors.
• Chemical Intermediate: Serves as a sophisticated synthetic building block for the research and development of novel analgesic compounds and related pharmaceutical agents.
• Analytical Chemistry: Employed in the development and calibration of sensitive analytical methods, such as HPLC-MS and GC-MS, for detecting and quantifying fentanyl analogs.

Basic Information

Product Name	Trefentanil
CAS No.	120656-93-1
Molecular Formula	C₂₄H₃₀N₂O₃
Molecular Weight	394.51 g/mol
Synonyms	N-[1-(2-Phenylethyl)-4-piperidinyl]-N-phenylpropanamide; Trefentanil Hydrochloride; Fentanyl, 3-Methyl-; 3-Methylfentanyl; (±)-Trefentanil; 1-Phenethyl-4-(N-phenylpropionamido)piperidine; NIH 10618
EINECS	Contact for details

Quality Control

Our Trefentanil is manufactured under strict quality management systems to ensure the highest standards of purity and consistency. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the exact specifications and results. We adhere to relevant Good Manufacturing Practice (GMP) principles for active pharmaceutical ingredients (APIs) and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product should be kept under an inert atmosphere if long-term stability is required and handled in accordance with all applicable safety regulations for potent compounds.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.