Description

2-Hydroxy-Thiazole-5-Carboxylic Acid Ethyl Ester is a versatile heterocyclic building block and ester derivative of significant interest in advanced organic synthesis. Its core value lies in its functionalized thiazole scaffold, which serves as a critical precursor for the development of complex molecules with targeted biological and material properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to construct novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly those targeting infectious diseases, inflammation, and metabolic disorders.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole moiety.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized ligands used in coordination chemistry and catalysis.
• Material Science: Employed in the research of organic semiconductors, dyes, and photoactive materials due to its conjugated system.
• Chemical Biology Probes: Utilized to build molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A fundamental building block for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	2-Hydroxy-Thiazole-5-Carboxylic Acid Ethyl Ester
CAS No.	120647-10-1
Molecular Formula	C6H7NO3S
Molecular Weight	173.19 g/mol
Synonyms	Ethyl 2-hydroxy-1,3-thiazole-5-carboxylate; 5-Thiazolecarboxylic acid, 2-hydroxy-, ethyl ester; 2-Hydroxythiazole-5-carboxylic acid ethyl ester; 2-Hydroxy-5-thiazolecarboxylic acid ethyl ester; Ethyl 2-hydroxythiazole-5-carboxylate; 5-(Ethoxycarbonyl)-2-hydroxythiazole; 2-Hydroxy-5-(ethoxycarbonyl)thiazole
EINECS	Contact for details

Quality Control

Every batch of 2-Hydroxy-Thiazole-5-Carboxylic Acid Ethyl Ester is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets your specific research or production requirements. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.