Description

5-(Trifluoromethyl)Isoquinoline is a high-value fluorinated heterocyclic building block essential for advanced organic synthesis. Its core value lies in the unique electronic and steric properties imparted by the trifluoromethyl group, which is critical for modulating the biological activity and physicochemical characteristics of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of potential drug candidates, particularly in kinase inhibitor and central nervous system (CNS) targeted therapies.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the CF3 group enhances lipophilicity and metabolic stability.
• Material Science Precursor: Serves as a building block for advanced organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Ligand Synthesis in Catalysis: Employed to create sophisticated nitrogen-containing ligands for transition metal catalysts used in cross-coupling and other fine chemical reactions.
• Fluorine Chemistry Research: A valuable substrate for studying nucleophilic substitution and other reactions on fluorinated heterocycles.

Basic Information

Item	Detail
Product Name	5-(Trifluoromethyl)Isoquinoline
CAS No.	120568-09-4
Molecular Formula	C10H6F3N
Molecular Weight	197.16 g/mol
Synonyms	5-(Trifluoromethyl)isoquinoline; Isoquinoline, 5-(trifluoromethyl)-; 5-Trifluoromethylisoquinoline; 120568-09-4; 5-CF3-Isoquinoline; α,α,α-Trifluoro-5-isoquinolinemethane
EINECS	Contact for details

Quality Control

Our 5-(Trifluoromethyl)Isoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.