Description

(R)-1-(2-Chlorophenyl)Ethanol is a high-purity chiral intermediate, specifically the (R)-enantiomer of 1-(2-chlorophenyl)ethanol. This compound is a critical building block in the synthesis of enantiomerically pure pharmaceuticals and fine chemicals, where its defined stereochemistry is essential for biological activity and process control. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for developing active pharmaceutical ingredients (APIs), chiral ligands, and specialty polymers.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Synthesis: Used as a chiral auxiliary or resolving agent in stereoselective organic synthesis to induce chirality in target molecules.
• Agrochemical Research: Serves as a precursor in the development of chiral pesticides and herbicides, where specific enantiomers often exhibit superior efficacy.
• Ligand and Catalyst Preparation: Employed in the synthesis of chiral ligands for transition metal catalysts used in homogeneous catalysis.
• Material Science: A monomer or modifier in the research of chiral polymers and liquid crystals with specialized optical properties.
• Academic & Process R&D: Used in universities and corporate R&D labs for method development, scale-up studies, and investigating new chiral transformations.

Basic Information

Product Name	(R)-1-(2-Chlorophenyl)Ethanol
CAS No.	120466-66-2
Molecular Formula	C8H9ClO
Molecular Weight	156.61 g/mol
Synonyms	(R)-1-(2-Chlorophenyl)ethanol; (R)-α-Methyl-2-chlorobenzyl alcohol; (R)-2-Chloro-α-methylbenzyl alcohol; (1R)-1-(2-Chlorophenyl)ethan-1-ol; (R)-(-)-1-(2-Chlorophenyl)ethanol; (R)-1-(o-Chlorophenyl)ethanol; (R)-o-Chloro-α-methylbenzyl alcohol
EINECS	Contact for details

Quality Control

Our (R)-1-(2-Chlorophenyl)Ethanol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess (ee), and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.