Description

2,5-Bis(4-Methoxyphenylhydroxymethyl)Thiophene is a specialized organic compound featuring a central thiophene ring symmetrically substituted with benzhydrol-type groups. This unique molecular architecture makes it a valuable intermediate for synthesizing advanced materials and fine chemicals. It is particularly relevant for researchers and manufacturers in the pharmaceutical and specialty chemical sectors seeking to develop novel compounds with specific electronic or structural properties.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system or inflammatory pathways.
• Liquid Crystal & OLED Material Precursor: Serves as a core structure for developing advanced organic electronic materials used in displays and lighting technologies.
• Polymer & Resin Modifier: Used to incorporate thiophene and aromatic units into polymer backbones to enhance thermal stability, optical properties, or mechanical strength.
• Organic Synthesis Reagent: Employed in asymmetric synthesis and cross-coupling reactions to construct complex, multi-functional organic molecules.
• Agrochemical Intermediate: Acts as a precursor in the development of new generation crop protection agents with novel modes of action.
• Research & Development: A critical compound for academic and industrial R&D in medicinal chemistry, materials science, and catalysis.

Basic Information

Item	Details
Product Name	2,5-Bis(4-Methoxyphenylhydroxymethyl)Thiophene
CAS No.	120450-72-8
Molecular Formula	C26H24O4S
Molecular Weight	432.53 g/mol
Synonyms	2,5-Bis[(4-methoxyphenyl)(hydroxy)methyl]thiophene; 2,5-Bis(α-Hydroxy-4-methoxybenzyl)thiophene; 2,5-Bis(4-Methoxybenzhydryl)thiophene; Thiophene-2,5-diylbis((4-methoxyphenyl)methanol); 1,1'-(Thiophene-2,5-diyl)bis(1-(4-methoxyphenyl)methanol); 2,5-Bis(4-methoxy-α-hydroxybenzyl)thiophene
EINECS	Contact for details

Quality Control

Our production of 2,5-Bis(4-Methoxyphenylhydroxymethyl)Thiophene adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your specifications. Our quality system is designed to support cGMP and ISO standards for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.