Description

4-Bromo-2-Ethylthiazole is a versatile brominated heterocyclic building block, a key intermediate in the synthesis of complex organic molecules. Its value lies in its reactive bromine atom and the thiazole core, which are essential for constructing pharmacologically active compounds and advanced materials. This high-purity intermediate is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing thiazole or substituted thiazole moieties.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the thiazole ring contributes to biological activity.
• Material Science Research: Serves as a precursor for the development of organic semiconductors, ligands for catalysis, and other functional organic materials.
• Chemical Biology & Proteomics: Employed as a reactive handle in the synthesis of chemical probes and bioconjugation reagents for studying biological systems.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to form complex biaryl structures.
• Ligand and Catalyst Development: Utilized to create novel nitrogen-sulfur (N,S) donor ligands for transition metal catalysis.

Basic Information

Product Name	4-Bromo-2-Ethylthiazole
CAS No.	120258-27-7
Molecular Formula	C5H6BrNS
Molecular Weight	192.08 g/mol
Synonyms	2-Ethyl-4-bromothiazole; 4-Bromo-2-ethyl-1,3-thiazole; Thiazole, 4-bromo-2-ethyl-; 2-Ethyl-4-bromo-1,3-thiazole; 4-Bromo-2-ethylthiazole; 120258-27-7 (CAS)
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Ethylthiazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.