Description

Bicyclo[2.1.1]Hexane, 2-Bromo- (9Ci) is a specialized brominated bicyclic hydrocarbon building block of significant interest in advanced organic synthesis. This compound matters for its unique, highly strained bicyclo[2.1.1]hexane framework, which serves as a valuable precursor for creating rigid, three-dimensional molecular scaffolds in medicinal chemistry and materials science. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring precise spatial control and novel structural motifs.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel active pharmaceutical ingredients (APIs) with enhanced three-dimensional complexity and metabolic stability.
• Agrochemical Research: Used in the development of new crop protection agents where the strained bicyclic core can impart unique biological activity and physical properties.
• Ligand and Catalyst Development: Serves as a precursor for creating sterically demanding, chiral ligands and organocatalysts used in asymmetric synthesis.
• Materials Science Precursor: Employed in the synthesis of monomers for advanced polymers with tailored rigidity, thermal stability, and optical properties.
• Chemical Biology Probe Synthesis: Utilized to construct molecular probes and tags with well-defined, compact geometries for studying biological systems.
• Cross-Coupling Reactions: Acts as an electrophilic partner in various metal-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi) to introduce the bicyclo[2.1.1]hexane moiety.

Basic Information

Product Name	Bicyclo[2.1.1]Hexane, 2-Bromo- (9Ci)
CAS No.	120159-43-5
Molecular Formula	C6H7Br
Molecular Weight	159.03 g/mol
Synonyms	2-Bromobicyclo[2.1.1]hexane; 2-Bromo-bicyclo[2.1.1]hexane; Bicyclo[2.1.1]hexane, 2-bromo-; 2-Bromotricyclo[2.1.1.01,4]hexane; 120159-43-5; 2-Bromo-1,4-methanobicyclo[2.1.1]hexane
EINECS	Contact for details

Quality Control

Our Bicyclo[2.1.1]Hexane, 2-Bromo- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We are committed to meeting the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.