Description

Mercaptomethyl-4-Methylpentanoyl-Phenylalanylalaninamide is a specialized peptide derivative containing a mercaptomethyl functional group. This compound is significant for its role as a key synthetic intermediate or building block in advanced pharmaceutical research and development. It is primarily needed by researchers and manufacturers in the pharmaceutical and biotechnology sectors for applications such as drug discovery, proteomics, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel peptide-based drug candidates and active pharmaceutical ingredients (APIs).
• Protease Inhibitor Research: Used in the development and study of enzyme inhibitors, particularly targeting proteases, due to its peptide backbone and reactive thiol group.
• Chemical Biology Probes: Serves as a precursor for creating labeled probes to study protein-protein interactions and enzyme mechanisms.
• Conjugation Chemistry: The mercaptomethyl group enables site-specific conjugation for creating antibody-drug conjugates (ADCs) or peptide-drug conjugates.
• Peptide Library Synthesis: Employed in combinatorial chemistry for generating diverse peptide libraries for high-throughput screening.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic assays and biochemical pathway studies.

Basic Information

Item	Details
Product Name	Mercaptomethyl-4-Methylpentanoyl-Phenylalanylalaninamide
CAS No.	119935-96-5
Molecular Formula	C₂₁H₃₁N₃O₄S
Molecular Weight	421.55 g/mol
Synonyms	Mercaptomethyl-4-methylpentanoyl-Phe-Ala-NH₂; (S)-2-((S)-2-((2-((2-Mercaptoethyl)thio)-4-methylpentanoyl)amino)-3-phenylpropanamido)propanamide; 4-Methyl-2-[(2-sulfanylethyl)sulfanyl]pentanoic acid - L-phenylalanyl-L-alaninamide (1:1); A building block peptide with a thiol-containing side chain.
EINECS	Contact for details

Quality Control

Our Mercaptomethyl-4-Methylpentanoyl-Phenylalanylalaninamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep the container in a dry, well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.