Description

Ethyl 2-(4-Bromobenzamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular scaffolds. It is primarily sought after by research institutions, custom synthesis laboratories, and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of target drug molecules, especially those with tetrahydrobenzo[b]thiophene cores.
• Drug Discovery & Medicinal Chemistry: Used in research and development for constructing compound libraries and exploring structure-activity relationships (SAR) in new therapeutic candidates.
• Custom Synthesis & Contract Manufacturing: Employed by CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and non-commercial API batches for clinical trials.
• Chemical Research: Acts as a specialized reagent in academic and industrial research focused on heterocyclic chemistry and organosulfur compound synthesis.

Basic Information

Product Name	Ethyl 2-(4-Bromobenzamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate
CAS No.	119934-21-3
Molecular Formula	C18H18BrNO3S
Molecular Weight	408.31 g/mol
Synonyms	Ethyl 2-[(4-bromobenzoyl)amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate; 2-(4-Bromobenzamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic Acid Ethyl Ester; 4,5,6,7-Tetrahydro-2-[[(4-bromophenyl)carbonyl]amino]benzo[b]thiophene-3-carboxylic Acid Ethyl Ester; Benzo[b]thiophene-3-carboxylic acid, 2-[(4-bromobenzoyl)amino]-4,5,6,7-tetrahydro-, ethyl ester
EINECS	Contact for details

Quality Control

Our production of Ethyl 2-(4-Bromobenzamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and purity suitable for research and pharmaceutical applications. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.