Description

2-Deoxy-D-[6-13C]Arabino-Hexose is a stable isotope-labeled analog of 2-deoxy-D-glucose, where the carbon-6 position is enriched with the 13C isotope. This precise labeling makes it an indispensable tool for advanced metabolic research and tracer studies, providing critical insights into glucose metabolism and related biochemical pathways. It is primarily utilized by research institutions, pharmaceutical developers, and diagnostic companies engaged in metabolomics, drug discovery, and the study of metabolic disorders such as cancer.

Application

• Metabolic Tracer Studies: Used in Nuclear Magnetic Resonance (NMR) spectroscopy and Mass Spectrometry (MS) to trace and quantify glucose uptake and glycolytic flux in cells and tissues.
• Drug Discovery & Development: Serves as a key reagent in screening and validating compounds that target glucose metabolism, a hallmark of many cancers.
• Biomedical Research: Enables detailed investigation of metabolic pathways in neuroscience, cardiology, and endocrinology research.
• Diagnostic Agent Development: Acts as a precursor for developing advanced Positron Emission Tomography (PET) imaging probes, such as [18F]FDG analogs, for clinical diagnostics.
• Enzyme Mechanism Studies: Employed to elucidate the catalytic mechanisms of hexokinases and other glycolytic enzymes using isotopic labeling.

Basic Information

Product Name	2-Deoxy-D-[6-13C]Arabino-Hexose
CAS No.	119897-50-6
Molecular Formula	C6H12O5 (with 13C at C-6)
Molecular Weight	165.15 g/mol (13C labeled)
Synonyms	2-Deoxy-D-[6-13C]glucose; 2-Deoxy-D-arabino-hexose-6-13C; 6-13C-2-Deoxy-D-glucose; 2-Deoxy-D-glucose-6-13C; D-[6-13C]-2-Deoxyglucose; 13C Labeled 2-DG; Isotopic 2-Deoxyglucose; 2-DG-6-13C
EINECS	Contact for details

Quality Control

Every batch of 2-Deoxy-D-[6-13C]Arabino-Hexose is manufactured and tested under strict quality systems. We guarantee high chemical and isotopic purity, verified by advanced analytical techniques including NMR and HPLC-MS. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing purity, isotopic enrichment, and solvent residues. Our quality commitment ensures reliability for your most sensitive research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (13C)	≥ 99 atom %
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.