Description

3-Amino-5-Bromoindolin-2-One Hydrochloride is a high-purity, halogenated indolinone derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmaceutical intermediate and building block for the development of novel bioactive molecules. It is primarily utilized by research institutions and chemical manufacturers in the pharmaceutical, agrochemical, and life science sectors for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Organic Synthesis Building Block: Used for constructing indole and indoline-based scaffolds in medicinal chemistry and material science research.
• Agrochemical Research: Serves as a starting material for developing new crop protection agents and herbicides.
• Biochemical Research: Employed in the study of enzyme inhibitors and receptor ligands due to its specific molecular structure.
• Chemical Reference Standard: Used for analytical method development, validation, and quality control in laboratory settings.

Basic Information

Product Name	3-Amino-5-Bromoindolin-2-One Hydrochloride
CAS No.	119884-84-3
Molecular Formula	C8H8BrN2O·HCl
Molecular Weight	265.53 g/mol (Free base: 228.07 g/mol)
Synonyms	5-Bromo-3-aminoindolin-2-one hydrochloride; 3-Amino-5-bromo-2-indolinone hydrochloride; 5-Bromo-3-amino-2-oxindole hydrochloride; 2-Oxindole, 3-amino-5-bromo-, hydrochloride; 3-Amino-5-bromo-1,3-dihydro-2H-indol-2-one hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Amino-5-Bromoindolin-2-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.