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Decanoyl n-(Methyl-D3)3-Carnitine CAS NO 119766-69-7
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CAS No.:119766-69-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Decanoyl n-(Methyl-D3)3-Carnitine is a deuterium-labeled analog of decanoyl-L-carnitine, a key intermediate in fatty acid metabolism. This compound is specifically designed for use as an internal standard in quantitative mass spectrometry, providing superior accuracy and reliability in analytical workflows. It is an essential tool for researchers and quality control laboratories in the pharmaceutical, biotechnology, and clinical diagnostics sectors who require precise measurement of acylcarnitine levels for metabolic studies, drug development, and biomarker discovery.
Application
- Mass Spectrometry Internal Standard: Primary application as a stable isotope-labeled internal standard for the accurate quantification of endogenous decanoyl-L-carnitine in LC-MS/MS and GC-MS analyses.
- Metabolomics & Biomarker Research: Critical for targeted metabolomic profiling to study disorders of fatty acid oxidation (FAOD) and other inborn errors of metabolism.
- Pharmaceutical R&D: Used in pharmacokinetic (PK) and pharmacodynamic (PD) studies to track drug-induced changes in acylcarnitine profiles.
- Clinical Diagnostics: Enables precise calibration in newborn screening and diagnostic assays for conditions like medium-chain acyl-CoA dehydrogenase (MCAD) deficiency.
- Nutritional Science: Supports research into the role of carnitine and its esters in energy metabolism, exercise physiology, and nutritional supplements.
- Quality Control & Method Validation: Essential for developing, validating, and ensuring the compliance of analytical methods in GLP/GMP environments.
Basic Information
| Product Name | Decanoyl n-(Methyl-D3)3-Carnitine |
| CAS No. | 119766-69-7 |
| Molecular Formula | C18H32D3NO4 |
| Molecular Weight | 334.48 g/mol |
| Synonyms | Decanoyl-L-carnitine (methyl-D3); (3R)-3-(Decanoyloxy)-4-(trimethyl-d9-ammonio)butanoate; L-Carnitine decanoate ester (methyl-D3); 10:0 Carnitine-d3; Decanoylcarnitine-d3; D3-Decanoyl-L-carnitine; Deuterated Decanoyl Carnitine Internal Standard; Caprinoyl-L-carnitine-d3 |
| EINECS | Contact for details |
Quality Control
Our Decanoyl n-(Methyl-D3)3-Carnitine is manufactured under strict quality systems to ensure the high chemical and isotopic purity required for analytical standards. Each batch is characterized by advanced spectroscopic and chromatographic techniques, including NMR, HPLC, and mass spectrometry, to confirm identity, isotopic enrichment, and purity. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet the requirements of GMP, GLP, and ISO 17025 accredited laboratories.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere to maintain stability and purity. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (HPLC-MS) | Conforms |
| Identification (NMR) | Conforms |
| Purity (HPLC) | ≥ 95% |
| Isotopic Enrichment | ≥ 98 atom % D |
| Chemical Purity (by NMR) | ≥ 97% |
| Water Content (KF) | ≤ 1.0% |
| Residual Solvents (GC) | Meets ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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