Description

tert-Butyl (4-Bromothiophen-3-Yl)Carbamate is a high-purity, protected amine derivative that serves as a critical synthetic intermediate in advanced organic chemistry. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for use in medicinal chemistry, process development, and custom synthesis projects.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those containing functionalized thiophene scaffolds.
• Medicinal Chemistry Research: Used in parallel and combinatorial synthesis for lead optimization and structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Serves as a precursor in the development of new pesticides and herbicides that require brominated heterocyclic components.
• Material Science: Employed in the synthesis of organic semiconductors, conductive polymers, and other advanced materials where the thiophene unit is essential.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and contract research organizations (CROs/CMOs) producing specialized fine chemicals.
• Academic Research: Used in university and institutional labs for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	tert-Butyl (4-Bromothiophen-3-Yl)Carbamate
CAS No.	119485-57-3
Molecular Formula	C9H12BrNO2S
Molecular Weight	278.17 g/mol
Synonyms	Boc-4-Bromo-3-aminothiophene; 3-((tert-Butoxycarbonyl)amino)-4-bromothiophene; 4-Bromo-3-((tert-butoxycarbonyl)amino)thiophene; tert-Butyl N-(4-bromothiophen-3-yl)carbamate; N-Boc-4-bromo-3-aminothiophene; 4-Bromo-3-aminothiophene N-Boc derivative; (4-Bromothiophen-3-yl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl (4-Bromothiophen-3-Yl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment. We adhere to cGMP principles for pharmaceutical intermediates, ensuring traceability and documentation for regulatory support.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.