Description

Danofloxacin Mesylate is a synthetic fluoroquinolone antibiotic specifically formulated as the mesylate salt to enhance solubility and bioavailability. This compound is of critical importance in veterinary medicine for its potent bactericidal activity against a broad spectrum of Gram-negative and Gram-positive pathogens. It is primarily needed by manufacturers in the animal health sector for the formulation of effective therapeutic solutions for respiratory and systemic infections in livestock and poultry.

Application

• Veterinary Pharmaceutical Formulations: Primary active ingredient in injectable solutions and premixes for the treatment of bacterial diseases.
• Poultry Health Management: Used to combat respiratory infections like avian colibacillosis and mycoplasmosis in broilers and layers.
• Livestock Therapeutics: Treatment of bovine and swine respiratory disease (BRD and SRD) and other systemic bacterial infections.
• Aquaculture: Potential application in controlling bacterial infections in farmed fish, subject to regional regulatory approvals.
• API Intermediate: Serves as a key chemical entity for further synthesis and research in antimicrobial development.
• Research & Development: Used in microbiological and pharmacological studies to understand fluoroquinolone efficacy and resistance mechanisms.

Basic Information

Product Name	Danofloxacin Mesylate
CAS No.	119478-55-6
Molecular Formula	C19H20F3N3O3 • CH4O3S
Molecular Weight	489.47 g/mol
Synonyms	Danofloxacin Methanesulfonate; 1-Cyclopropyl-6-fluoro-7-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept-2-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid methanesulfonate; ADVOCIN; ADVOCIN A 180; S-(-)-9-Fluoro-6,7-dihydro-8-(4-methyl-1-piperazinyl)-5-methyl-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acid methanesulfonate; CP 76,136-27; Danofloxacin mesilate; Danofloxacin mesylate salt
EINECS	Contact for details

Quality Control

Our Danofloxacin Mesylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing parameters such as assay, related substances, residual solvents, and microbiological quality. We adhere to cGMP principles to ensure supply reliability and batch-to-batch consistency for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Heavy Metals	≤ 20 ppm
Microbial Limits	Conforms to EP/USP requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.