Description

tert-Butyl-[(Ethylthio)Methoxy]dimethylsilane is a specialized organosilicon compound featuring a unique tert-butyl-dimethylsilyl (TBDMS) protecting group linked via a sulfur-containing methoxy bridge. This molecular architecture makes it a valuable reagent in advanced synthetic chemistry, particularly for the protection of sensitive functional groups under challenging conditions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Advanced Pharmaceutical Intermediates: Serves as a key protecting group reagent in the multi-step synthesis of active pharmaceutical ingredients (APIs), especially where standard silylating agents are insufficient.
• Agrochemical Synthesis: Employed in the production of novel pesticides and herbicides, where its stability can be leveraged in harsh synthetic sequences.
• Organic Synthesis & Process Chemistry: Used as a versatile silicon-based building block for constructing complex organic molecules in academic and industrial R&D laboratories.
• Material Science Precursor: Acts as a precursor in the development of specialty silicones or surface-modifying agents with specific thioether functionalities.
• Peptide & Oligonucleotide Chemistry: Potential application in protecting hydroxyl groups during solid-phase synthesis of sensitive biomolecules.

Basic Information

Product Name	tert-Butyl-[(Ethylthio)Methoxy]dimethylsilane
CAS No.	119451-79-5
Molecular Formula	C9H22OSSi
Molecular Weight	206.42 g/mol
Synonyms	tert-Butyldimethyl[(ethylthio)methoxy]silane; [(Ethylthio)methoxy](tert-butyl)dimethylsilane; (Ethylthiomethoxy)(tert-butyl)dimethylsilane; TBDMS ethylthiomethyl ether; Silane, [(ethylthio)methoxy](1,1-dimethylethyl)dimethyl-; 1-((tert-Butyldimethylsilyl)oxy)methylthio)ethane
EINECS	Contact for details

Quality Control

Every batch of tert-Butyl-[(Ethylthio)Methoxy]dimethylsilane is produced and tested under strict quality management protocols to ensure consistency and purity for demanding synthetic applications. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.