Description

Methyl 1,3-Dimethyl-2,4-Dioxo-2,3,4,7-Tetrahydro-1H-Pyrrolo[2,3-D]Pyrimidine-6-Carboxylate, 96% is a high-purity heterocyclic building block and key synthetic intermediate. This compound is valued for its role in constructing complex molecular architectures, particularly in advanced pharmaceutical research and development. It is essential for medicinal chemists and process development scientists working on novel therapeutic agents, including kinase inhibitors and other targeted small molecule drugs.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitor candidates.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Biology Probes: Used in the development of tool compounds and probes for studying biological pathways and target validation.
• Process Chemistry: Employed in route scouting and scale-up synthesis for the commercial manufacturing of complex heterocyclic molecules.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	Methyl 1,3-Dimethyl-2,4-Dioxo-2,3,4,7-Tetrahydro-1H-Pyrrolo[2,3-D]Pyrimidine-6-Carboxylate, 96%
CAS No.	119350-50-4
Molecular Formula	C11H13N3O4
Molecular Weight	251.24 g/mol
Synonyms	Methyl 1,3-dimethyl-2,4-dioxo-1,2,3,4,7,8-hexahydropyrrolo[2,3-d]pyrimidine-6-carboxylate; 1,3-Dimethyl-2,4-dioxo-2,3,4,7-tetrahydro-1H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid methyl ester; 6-Methoxycarbonyl-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-7H-pyrrolo[2,3-d]pyrimidine; 1,3-Dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 1,3-Dimethyl-2,4-Dioxo-2,3,4,7-Tetrahydro-1H-Pyrrolo[2,3-D]Pyrimidine-6-Carboxylate, 96% is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of pharmaceutical R&D and cGMP environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 96.0%
Related Substances (HPLC)	Total impurities ≤ 4.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.