Description

3-Amino-4,5,6,7-tetrahydro-benzo[b]thiophene-2-carboxylic acid methyl ester is a high-purity, heterocyclic organic building block of significant synthetic utility. This compound is valued for its role as a versatile intermediate in the synthesis of complex pharmacologically active molecules. It is primarily sought by research and development teams, as well as production chemists, in the pharmaceutical and agrochemical industries for constructing novel thiophene-based scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates targeting central nervous system (CNS) disorders, cardiovascular diseases, and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiophene moiety.
• Material Science Research: Serves as a building block for organic semiconductors, conductive polymers, and advanced organic materials due to its electron-rich thiophene core.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new heterocyclic chemistry, reaction methodologies, and structure-activity relationships (SAR).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and non-commercial scale-up projects.

Basic Information

Product Name	3-Amino-4,5,6,7-tetrahydro-benzo[b]thiophene-2-carboxylic acid methyl ester
CAS No.	119205-38-8
Molecular Formula	C10H13NO2S
Molecular Weight	211.28 g/mol
Synonyms	Methyl 3-amino-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxylate; 3-Amino-4,5,6,7-tetrahydrobenzo[b]thiophene-2-carboxylic acid methyl ester; 2-Carbomethoxy-3-amino-4,5,6,7-tetrahydrobenzo[b]thiophene; Methyl 3-amino-4,5,6,7-tetrahydrobenzo[b]thiophene-2-carboxylate; 3-Amino-4,5,6,7-tetrahydro-2-benzothiophenecarboxylic acid methyl ester; 119205-38-8; 3-Amino-4,5,6,7-tetrahydrobenzo[b]thiophene-2-methyl carboxylate
EINECS	Contact for details

Quality Control

Our 3-Amino-4,5,6,7-tetrahydro-benzo[b]thiophene-2-carboxylic acid methyl ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.