Description

4-Aminobenzoic-2,6-D2 Acid is a deuterium-labeled isotopologue of para-aminobenzoic acid (PABA), a key biochemical building block. This compound is specifically designed for use as an internal standard in mass spectrometry and as a tracer in metabolic and pharmacokinetic studies, offering superior analytical precision. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and analytical chemistry sectors who require high-fidelity labeled compounds for advanced R&D and quality control.

Application

• Mass Spectrometry Internal Standard: Used for the accurate quantification of PABA and related compounds in complex biological matrices via LC-MS and GC-MS.
• Metabolic Pathway Tracing: Serves as a stable, non-radioactive tracer in drug metabolism studies (DMPK) and biochemical research.
• Pharmaceutical Reference Standard: Employed in the development and validation of analytical methods for drug substances and impurities.
• Isotope Dilution Analysis: Critical for achieving high accuracy and precision in quantitative analysis across environmental and food testing labs.
• Chemical Synthesis Intermediate: Acts as a labeled precursor for the synthesis of more complex deuterated molecules for research.

Basic Information

Product Name	4-Aminobenzoic-2,6-D2 Acid
CAS No.	118872-62-1
Molecular Formula	C7H5D2NO2
Molecular Weight	139.15 g/mol
Synonyms	PABA-2,6-d2; 4-Amino-D2-benzoic Acid; Deutero-PABA; 2,6-Dideutero-4-aminobenzoic Acid; Vitamin Bx-d2; para-Aminobenzoic-2,6-D2 Acid; 4-Carboxy-2,6-D2-aniline; Aminobenzoic Acid-d2
EINECS	Contact for details

Quality Control

Our 4-Aminobenzoic-2,6-D2 Acid is produced under strict quality management systems to ensure batch-to-batch consistency and high isotopic purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing parameters such as chemical purity, isotopic enrichment (D-atom %), and impurity profile. We support compliance with relevant pharmacopeial standards for reference materials, and custom specifications for research use are available.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-atom %)	≥ 98.0% (by 1H-NMR or MS)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.