Description

Nalbuphine 3-Acetylsalicylate is a pharmaceutical salt formed from the opioid analgesic nalbuphine and acetylsalicylic acid (aspirin). This compound is designed to combine the potent analgesic properties of nalbuphine with the anti-inflammatory and antipyretic effects of aspirin, offering a potential dual-mechanism approach to pain management. It is primarily utilized in advanced pharmaceutical research and development for creating novel analgesic formulations. This product is critical for researchers and manufacturers focused on developing next-generation pain relief medications with improved efficacy profiles.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced analgesic drug candidates.
• Analgesic Research: Used in preclinical and clinical research to study combined opioid and NSAID mechanisms for pain relief.
• Formulation Development: Employed in the development of controlled-release, combination pain management tablets or injectables.
• Reference Standard: Acts as a high-purity chemical reference standard for quality control and analytical method development in pharmaceutical labs.
• Pharmacological Studies: Utilized in studies investigating the synergistic effects, pharmacokinetics, and safety profiles of dual-action analgesics.

Basic Information

Product Name	Nalbuphine 3-Acetylsalicylate
CAS No.	118776-11-7
Molecular Formula	C31H35NO7
Molecular Weight	533.62 g/mol
Synonyms	Nalbuphine Aspirin Salt; Nalbuphine Acetylsalicylate; 17-(Cyclobutylmethyl)-4,5α-epoxy-3,14-dihydroxymorphinan-6-one 3-(2-Acetoxybenzoate); Nalbuphine 3-O-acetylsalicylate; Nalbuphine acetylsalicylate ester; Nubain Aspirin Salt (informal); Nalbuphine 3-(acetyloxy)benzoate
EINECS	Contact for details

Quality Control

Our Nalbuphine 3-Acetylsalicylate is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for pharmaceutical research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP (current Good Manufacturing Practice) guidelines where applicable, and our quality control protocols include stringent analytical testing to meet the exacting standards of the pharmaceutical industry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.