Description

Sarcosine-Methyl-D3 CAS NO 118685-91-9 is a stable isotope-labeled analog of sarcosine, where three deuterium atoms replace the three hydrogen atoms in the methyl group. This compound is a critical tool in advanced analytical chemistry, providing an internal standard for precise quantification and metabolic pathway tracing. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and life science industries who require high-fidelity data for method development, pharmacokinetic studies, and proteomics research.

Application

• Internal Standard for Quantitative Analysis: Used as a stable isotope-labeled internal standard in LC-MS and GC-MS methods for the accurate quantification of sarcosine and related metabolites in complex biological matrices.
• Metabolic Pathway Research: Employed in tracer studies to investigate glycine and one-carbon metabolism, providing insights into disease mechanisms and drug effects.
• Pharmaceutical Development: Facilitates drug metabolism and pharmacokinetics (DMPK) studies for new chemical entities, aiding in biomarker discovery and validation.
• Proteomics and Metabolomics: Serves as a crucial reagent in high-throughput screening and profiling to identify and quantify small molecule biomarkers.
• Agrochemical Research: Applied in environmental fate studies and residue analysis of compounds that metabolize through sarcosine-related pathways.
• Diagnostic Assay Development: Used in the calibration and validation of clinical diagnostic tests targeting metabolic disorders.

Basic Information

Product Name	Sarcosine-Methyl-D3
CAS No.	118685-91-9
Molecular Formula	C3D3H4NO2
Molecular Weight	92.10 g/mol
Synonyms	N-Methyl-D3-glycine; (Methyl-D3)aminoacetic acid; Sarcosine-D3; Deuterated Sarcosine; N-Methylglycine-methyl-D3; 2-[(Methyl-D3)amino]acetic acid; (Carboxymethyl)(methyl-D3)amine; NSC 113019-D3
EINECS	Contact for details

Quality Control

Our Sarcosine-Methyl-D3 is manufactured under strict quality control protocols to ensure exceptional isotopic purity and chemical integrity. Each batch is characterized using advanced analytical techniques, including NMR and Mass Spectrometry, to confirm isotopic enrichment and chemical purity. Certificates of Analysis (COA) detailing isotopic purity (e.g., D ≥ 98%), chemical purity (by HPLC), and specific analytical data are provided with every shipment. We adhere to cGMP principles for the production of high-value reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.