Description

2-Bromo-1-(5-Chloro-3-Methylbenzo[B]Thiophen-2-Yl)Ethan-1-One is a high-purity, synthetically valuable organic building block characterized by its halogenated benzothiophene core. This compound is critically important as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel active compounds.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its halogenated heterocyclic structure for bioactivity.
• Material Science: Acts as a building block for creating organic semiconductors, liquid crystals, and other functional materials due to its electron-rich benzothiophene unit.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and as an electrophile in nucleophilic substitution reactions to introduce complex molecular fragments.
• Academic & Contract Research: Essential for medicinal chemistry programs in universities and Contract Research Organizations (CROs) exploring new chemical entities.

Basic Information

Product Name	2-Bromo-1-(5-Chloro-3-Methylbenzo[B]Thiophen-2-Yl)Ethan-1-One
CAS No.	118337-33-0
Molecular Formula	C11H8BrClOS
Molecular Weight	303.60 g/mol
Synonyms	2-Bromo-1-(5-chloro-3-methyl-1-benzothiophen-2-yl)ethanone; 2-Bromo-1-(5-chloro-3-methylbenzo[b]thiophen-2-yl)ethan-1-one; 1-(5-Chloro-3-methylbenzo[b]thiophen-2-yl)-2-bromoethanone; 2-Bromo-1-(5-chloro-3-methylbenzo[b]thien-2-yl)ethanone; 5-Chloro-3-methyl-2-acetylbenzothiophene α-bromo ketone; α-Bromo-5'-chloro-3'-methyl-2-acetylthiophene
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-(5-Chloro-3-Methylbenzo[B]Thiophen-2-Yl)Ethan-1-One is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We employ advanced analytical techniques including HPLC, GC-MS, and NMR to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each batch to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep away from strong acids/bases and oxidizing agents. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.